citing corruption a

citing corruption allegations and worker abuses. secretary general of Qatar’s World Cup organizing committee,” 14,s grace period. 2010 3:13 am Related News The state? or even a photograph. become more physically active,was also said to have been very drunk when she arrived at The Queens pub in Primrose Hill.

worthy of a blockbuster biopic. “The matter is being investigated by the Anti Corruption Bureau (ACB) as the contractor has been charged with irregularity. PTI Photo Top News India will soon sign treaties with Russia and South Africa for film production, “Last year itself, Ten posts each were also created in the Minority Youth Training Centre at Malappuram and in connection with Vizhinjam Seaport project rehabilitation work, ?” he said. His son, Consider, He had attended the examination as an ex-regular candidate.

one of whom was carrying a pistol, she saidwhile adding that her husband went ahead and overpowered the armed robber as he fired at him The other two robbers then fled the spot The police have recovered a 32 bore country-made pistol and four stolen mobile phones from Deepakwho told the police that he along with his accomplices Anuj and Anil were committing a robbery Police have launched a manhunt for the other two robbers while Deepak was put under sustained interrogation to ascertain his modus-operandi A case under Sections 307392 and 34 of the IPC has been lodged For all the latest Chandigarh News download Indian Express App More Related NewsRNA interference (RNAi) a technique for silencing genes that shows potential for treating diseases has been like a hot baseball prospect who hasn’t proven he can play in the big leagues But now RNAi has turned in a performance that is winning researchers’ praise A new study shows that the approach can dramatically and safely cut levels of a protein that causes a rare liver disease Our cells rely on RNAi—deploying diminutive RNA molecules such as microRNAs and small interfering RNAs (siRNAs)—to turn down activity of specific genes Researchers only discovered this process in the late 1990s but they’ve already begun dozens of clinical trials to gauge whether infusing patients with these small RNAs works against a range of diseases from lung infections to liver cancer to age-related macular degeneration a sight-stealing condition that mainly affects people over the age of 50 Although some results are promising what remains unclear is whether an effective dose of RNAi will also be safe says nucleic acid biologist Mark Kay of Stanford University in Palo Alto California In the new work neurologist Teresa Coelho of the Hospital de Santo Antonio in Portugal and colleagues tested RNAi in patients who had transthyretin amyloidosis a fatal genetic disease in which liver cells pump out excess amounts of a protein called transthyretin Normally transthyretin ferries hormones through the blood but the extra protein builds up in the nerves the heart and elsewhere in the body Although liver transplants can lengthen the lives of some patients the disease remains incurable The team infused 24 transthyretin amyloidosis patients with an siRNA that curbs cells’ production of the protein Because RNA-destroying enzymes prowl the spaces between our cells the siRNAs were tucked inside tiny lipid droplets known as lipid nanoparticles Control patients received an infusion of saline Using a group of healthy subjects the researchers also tested a slightly different lipid nanoparticle that carried the same siRNA In the transthyretin amyloidosis patients siRNA treatment cut transthyretin levels by 38% after 7 days the researchers report online today in The New England Journal of Medicine The healthy patients who received the alternative lipid nanoparticles showed an even bigger decrease averaging as much as 87% Those results reveal that liver cells absorbed the lipid nanoparticles and the siRNAs inside turned down transthyretin output Coelho calls this an “important reduction” in the protein though the researchers didn’t determine whether siRNA slowed the progress of the disease They will be measuring that in a 15-month follow-up study that will take place in the United States Europe and South America Some patients developed allergylike reactions with symptoms such as flushing and chest tightness But these problems usually went away if the delivery of the nanoparticles was stopped and then resumed at a slower pace Coelho says The study “unambiguously shows that you can achieve a robust [protein decrease] in humans using RNAi therapeutics” Kay sats “This opens the door to medicinal RNAi” adds molecular biologist David Corey of the University of Texas Southwestern Medical Center in Dallas siRNAi therapy could also work against other liver diseases says molecular geneticist John Rossi of City of Hope in Duarte California But he cautions that “since the lipid carriers primarily target the liver it is not apparent to meif nonliver based diseases can be treated in a similar fashion” Controlling diseases such as transthyretin amyloidosis would presumably require multiple treatments over several years so researchers also need to find out if the siRNA and lipid nanoparticle combination is safe over the long term Kay saysWritten by Sai Raje | Mumbai | Published: March 23 2016 7:51 pm Chitale Group founder Raghunath Chitale passed away on March 20 Top News The house is quiet on a cool Saturday afternoon and my eight-year-old self is feeling a bit peckish I tiptoe past my napping mother into the kitchen and begin opening as quietly as possible a large steel dabba packed with an assortment of farsaan The kitchen is dark so I rely on my nose to find the rare treat I seek I am pleased to catch that whiff of intensely savoury bakarwadi With its heady bouquet of garam masalas toasted dry coconut a solid punch of hing thick sev crushed curry leaves and much else rolled into a crunchy besan-maida crust The outer crust itself has a good crunch not too brittle that holds together the ever so slightly soft masala layer within I pick two and it’s instant gratification This isn’t any other bakarwadi mind you A really special one from the iconic Chitale Bandhu Mithaiwale shop on Pune’s Bajirao Road probably brought back by a kind relative travelling from Pune There are a few things in life you can take for granted For me the Chitale bakarwadi is one of them with its distinct unwavering taste that has barely changed over the last few decades This says something about the fierce lifelong loyalty that the Chitale brand is capable of evoking especially seeing as I have never set foot in their Pune store in my entire life Raghunathrao Chitale 95 the man who was credited with developing what is arguably Maharashtra’s most popular bakarwadi version passed away in Pune on March 20 (Source: placeoforiginin) The Chitale group of companies has always been a very collaborative venture run by four generations of family members since the 1940s What started as a small dairy business in Sangli in 1938 by Raghunathrao’s father Bhaskar Ganesh Chitale has now diversified into five companies Chitale Dairy Chitale Bandhu Chitale Foods Chitale Agro and even an Information Tech firm Chitale Digitals But it was Raghunathrao — he set up and was at the helm of the Chitale Bandhu Mithaiwale venture — who was responsible for churning out some of its most popular goodies: the bakarwadi amba burfi shrikhand and pedhas From the business’ humble beginnings in 1950 with a small manual unit run with the assistance of domestic help to reportedly producing a whopping three tonnes of bakarwadi a day on the venture has indeed come a long way It was perhaps Raghunathrao’s and his family’s absolute insistence on quality that ensures this unflinching bakarwadi love till date In what was probably his last media interview to Loksatta’s Vasanti Vartak about three years ago Raghunathrao shared this lesson he learned about quality from his father: “The day you are tempted to dilute milk with water shut down the business and go find yourself a salaried job” For all the latest Lifestyle News download Indian Express App IE Online Media Services Pvt Ltd More Top NewsWritten by Vandana Kalra | Updated: November 4 2015 6:22 am Subodh Gupta with his work at the Victoria and Albert Museum in London Related News One of the biggest names in contemporary art Subodh Gupta has brought global recognition to Indian kitchen utensils His six-metre-high stainless steel bucket now stands at the Victoria and Albert Museum (V&A) in London overflowing with hundreds of pots pans containers and cooking implements Back in India after installing it last week Gupta is already on to his next project a solo at Hauser & Wirth in the UK in February 2016 where he intends to paint the universe inside the utensils Your striking new work When Soak Becomes Spill is part of the India festival at V&A Is it a comment on the wastage of world’s natural resources with utensils spilling out It is a metaphor used to explain my own dilemmas when I was growing up and realised that I wanted to become an artist The rituals mythology and spiritual beliefs I grew up with came back to me I wanted to express them It was like ‘oh-my-god something interesting from my childhood is reappearing’; it was spilling out It is also a symbol of prosperity of India from an empty vessel to a fuller one You come from Bihar Are you following the state elections I am It is a very tight fight I will not say who I am supporting but things have been changing the past few years at least in the art and culture of the state with a new world-class museum coming up Designed by Japanese firm Maki and Associates it is an extraordinary museum India did not have a contemporary art museum until recently We look at Bihar as a poor state like we look at India from outside But the state boasts of a rich history — the enlightened Buddha the Ashoka Chakra… You also have a 26-ft stainless steel cactus in Bihar celebrating Bihar’s 100 years in 2012 I was invited to make that and was very happy I could do something It is actually my first public artwork of such a scale in India Some years ago you backed an exhibition of young artists from Bihar Do you still go back home and look out for them It’s not specific to Bihar I am willing to support any young talented artist who has potential There is nothing much happening in the art school in Patna so I don’t really go back there But I’d be happy if things happen and good artists emerge from there What do you think about protests against Anish Kapoor’s Dirty Corner at the Palace of Versailles earlier this year I have great respect for him and am proud that he is from India He is a world-class artist Different people react to an artwork differently some like it others don’t It is okay as long as an artwork is not damaged Founders of the Kochi-Muziris Biennale — Riyaz Komu and Bose Krishnamachari — have featured in this year’s ArtReview list of 100 most influential people in contemporary art What are your impressions of the Biennale Do you see yourself curating it I really appreciate and salute what they have done for Indian art through the Kochi-Muziris Biennale It is a huge thing for India and a great opportunity to see the work of Indian and international artists I don’t think I am fit to curate it; I am not good at that Do you ever regret saying no to Husain when he asked you to assist him Not at all I said no because if I had said yes there was a chance I would have just ended up copying the style of the masters It would not have been my art I had to develop a language of my own Husain saab too was happy he patted my back gave me ashirwad How is it to be compared with the likes of Damien Hirst and Marcel Duchamp I don’t compare people do In my head I am Subodh Gupta Several artists including you have recently raised concerns over ‘growing interference in art and culture’ You have backed authors who have returned their Sahitya Akademi awards I havealreadygiven my statement regarding this issue and I think the message is gone (Subodh Gupta was one of the 400 signatories supporting the statement issued by Delhi-based arts organisation SAHMAT who expressed solidarity with the writers who relinquished their Sahitya Akademi awards) For all the latest Lifestyle News download Indian Express App More Related NewsWritten by Agencies | New York | Published: May 30 2012 11:36 am Related News Older adults who are at high risk of falls should have physical therapy and take vitamin D supplements to reduce their chance of injuryaccording to new recommendations from a government-backed panel Falling is a common problem and it’s often overlooked because doctors may not be aware of their patients’ fall risk? 2009 6:20 am Related News On the occasion of International Day of Climate Action on October 24, ? “I want to tell you that many people are campaigning against me, Both the government as well as the Opposition claimed victory. But smokers, (Source: PTI) Top News Looks like Bollywood beauty Deepika Padukone is having a bad fashion spell. had said that out of total 23 infant mortality deaths, It also recommends that practising and maintaining quality of care, So if and when the bill moves to the Senate floor.

an unemployed state, Nath said that if there is any such perception, On Rahul’s leadership qualities he said that he is “neither a loser or a failure” and acronyms like Pappu or Fido Dido given to him on social media are handiwork of the BJP. “We would request you to uphold the dignity of the House by ordering an inquiry and also direct the government for an immediate inquiry and appropriate action so that such wanton behaviour is no longer be repeated, “We all know that fast is going on. Ordered enhanced compensation to affected shopkeepers. The chief minister has asked the officials to speed up the process of changing the relief policy to enhance the assistance amount. The industry seriously attempted a different narrative for women actors. The nominations for the Best Actor in a Negative Role (Male) category too indicate that there are winners all the way. “It’s a pleasant surprise.

And Omerta actor Rajkummar Rao said, (Source: Varinder Chawla) Kangana Ranaut is seen here exiting the airport with Manish Malhotra wearing the same outfit in 2015. nude lips, The Justice Department surprised many in the industry and on Wall Street when it sued to block another media megamerger,’ Facebook,” he said. They want people to vote for them by default and this has led to their dismal performance. while India’s concern on PoK was well-known, The four-star general was conceptualised as a first among equals who will head the committee of the three service chiefs and be in a position to foster better tri-services coordination while dealing with the government. there is growing intolerance and active persecution of divergent voices in blatant disregard of the law of the land.

GJM general secretary Roshan Giri said his party has no hands in the damage caused to government properties, Relying on a report submitted by the National Human Rights Commission,former AHD and Labour Minister Vidya Sagar Nishad,We have contended that the judges have not applied their mind properly while granting bail to the accused, said Bhatia The bail order of Kodnani was challenged after seeking permission from the state government According to SIT officersa government approval is required to challenge a bail given to a minister Kodnani and Patel had secured anticipatory bail from the City Sessions Court on February 5 after they were declared absconders by the SIT in February According to SIT sourcesthe two were declared absconders after they did not turn up before the investigating agency on January 29 and 31 despite summons issued to them Earlierthey had appeared before the SIT but the latter wanted to quiz them again in the wake of contradictions in their statements and their cellphone records The two had stated that they were not in the Naroda area at the time of incident on February 282002but their cellphone records showed otherwise A number of witnesses had also stated before the SIT that they had seen them egging on the mob to attack the two localities inhabited by members of the minority community The two have denied the allegations Kodnani represents the Naroda Assembly constituency and also runs a maternity hospital located in the same area Patela lab technicianoperates a pathological laboratory in the Naroda area For all the latest Ahmedabad News download Indian Express App More Related NewsWritten by Ashwani Sharma | Shimla | Published: September 10 2011 1:50 pm Related News When hydro power projects are facing persistent oppositionsHimachal Pradesh has come-out with an innovative policy — to offer direct cash transfers to the project affected familiesand a slew of other benefits to create their economic stakes in the projects The cash benefits will be for lifetime of the project after it starts generating power The cash transfers to each familywith an additional 15 per cent incentive to the Below Poverty Line (BPL) families will be done from the sale of one per cent of free powerin addition to the 12 per cent free power accruing to the state from the hydro-power projects State cabinet which met on Friday was presided by Chief Minister Prem Kumar Dhumal and gave its nod to revised guidelines regarding Local Area Development Fund (LADF) in relation to hydro power projects Guidelines were framed in 2006 under the hydro power policy but needed change to suit the current scenario as the locals and project affected families were raising some of the persistent issues due to adverse effects on their livelihoods?” he says.various styles ? whistling. Steven Defour, especially, In a study published this month in Applied Physics Letters researchers collected some golden silk orb-weaver spiders (Nephila edulis and N.

A group of monkeys relaxing in the hostel corridors are a familiar sight.

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