Tag: 夜上海论坛MI

FDA advisory panel recommends FluMist approval for young children

first_imgMay 17, 2007 (CIDRAP News) – A US Food and Drug Administration (FDA) advisory panel unanimously agreed Wednesday that FluMist, a nasal spray vaccine against seasonal flu, is safe and effective in children 2 years of age and older.The live-virus vaccine, which is manufactured by Gaithersburg, Maryland–based MedImmune, is already FDA-approved for 5- to 49-year-olds. The company has filed a supplemental biologics licensing application (sBLA) to expand its use to children younger than 5.In a 15-0 decision, the panel of outside experts supported the vaccine’s use for children 2 and older who do not have a history of wheezing. The FDA, which is expected to make a decision by the end of May, is not required to follow the panel’s recommendations.”The question remaining is how the FDA ultimately will rule on children under 2,” said MedImmune’s Chief Medical Officer Dr. Edward Connor, according to an Associated Press report.The panel voted 9-6 for the vaccine’s safety and benefits for children between 12 to 59 months without wheezing history and 12-3 against using the nasal spray in children between 6 to 23 months, according to a MedImmune press release.”The vote did demonstrate that there is a safety concern among a significant minority of the advisory committee,” Florence Houn, FDA deputy director of the office handling MedImmune’s application, told the Washington Post. “We do have to be careful about this respiratory adverse event profile and make sure we understand it.”A recent international study published in the New England Journal of Medicine showed children between 6 and 11 months who received FluMist had more hospitalizations and slightly more wheezing than those who got the standard vaccine, CIDRAP News reported in February. However, the same study, which was conducted in the 2004-2005 flu season, revealed 55% fewer cases of flu in the children who received the FluMist.CIDRAP Medical Director Kristine Moore, MD, MPH, said the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices recommends vaccination for children between 6 and 59 months because they have an increased risk for influenza-related hospitalizations and emergency room visits. Having a vaccine that is not a shot could enhance vaccination rates, Moore said.”It’s more tolerable to younger children,” she noted. “If FluMist is approved for this age-group, it would probably improve compliance to the CDC recommendation.”Currently only injectable inactivated vaccines are available for this group.FluMist vaccine has been on the market since 2003. It is effective against influenza A and B viruses; side-effects of the vaccine based on results from placebo-controlled clinical trials have included runny nose, sore throat, cough, headache, and chills.In January, the FDA also approved a refrigerated formulation of FluMist (previous formulations had to be frozen), which will be available for the 2007-2008 flu season, according to MedImmune.British company AstraZeneca is scheduled to acquire MedImmune in June in a $15.6 billion sale.See also:MedImmune Press ReleaseFeb 16, 2007, CIDRAP News story “Large study supports FluMist use in toddlers”2007 New England Journal of Medicine article [Abstract]last_img read more

Read More

Point-Counterpoint: Best Sports Couple

first_imgMcGrathI have to say, Cupid is a pretty awful judge of compatibility. I mean, this is the cherub who brought you Dennis Rodman and Carmen Electra, Andre “Bad Moon” Rison and Lisa “Left Eye” Lopez, the Benson’s, Mark Wohlers and ball four … the list goes on. Even when the fat, naked archer got it right, it was obviously a mistake … I mean, he was probably hungry.Without question, the best sports couple is Takeru Kobayashi and the hot dog. Do you know what kind of rock-solid foundation of love it would take for you to sit there and swallow 79,000 wieners and still come back with enough lust to want to gobble down 50 at each sitting? That’s dedication. And it’s reciprocal, too. The frankfurters, despite being notoriously cardiac unfriendly, haven’t had a bit of ill effect on Kobayashi to this point, as he is skinner than Manute Bol after a six-month fast. Take one look at the 420-pound Eric “Bad Lands” — that must mean the unfortunate earth that is underneath him at any given point in time — Booker and his physique fit for an oversized bean bag chair, and it is clear that the tube steak is showing the K-man some love.”Take”-out also has become a millionaire for his unique talent for guzzling down wieners like Lil’ Kim does … well, wieners. Meanwhile, Nathan’s hot dogs are still more popular than those stupid floppy-discs of beef served at most fast-food eateries, and dominate the attention of the American public on the most patriotic of days, the Fourth of July. Again, Cupid must’ve been aiming for Mary Kate Olson when he hit the gluttonous Kobayashi, but regardless he created a match made in Roman myth. Point: Hot dogs and Kobayashi. 2.14 PCP — PoppyPoppyThe best couple in the sports world should be one in which each side brings the best out in each other, and what better place to do that than the playing field?With that said, any athlete involving singer Toni Braxton is disqualified. Remember when she tore the Dallas Mavericks franchise apart in the mid-1990s by messing around with Jason Kidd, Jim Jackson and Jamal Mashburn?Anyway, the best couple in sports is none other than Ivan Rodriguez and Ugueth Urbina. Not to imply or disrespect anything homosexual, but seriously, the catcher-pitcher duo in baseball is one that requires a strong relationship, and Pudge and Ugi had just that.In 2003, Rodriguez and Urbina hooked up on the unlikeliest of teams, the Florida Marlins, and made history. Pudge had signed a one-year contract with the Marlins in hopes of reviving his career, and Ugi came on board mid-season as Florida found itself in the wildcard race. The battery connection posted solid seasons but made their magic in the postseason.As Rodriguez and Urbina opened the playoffs, they found their cupid in Steve Bartman, who in the single swift of one hand helped the couple on their way to the World Series, and it was there they showed everyone their true affection for one another.As Urbina recorded two saves against the Yankees, he and Rodriguez celebrated the Marlins’ victories with a smooch on the mound. It caused a stir in the sports world, but really it’s just an extension of the butt-smack.Rodriguez and Urbina even had a honeymoon of sorts, jumping ship to the lowly Tigers the next year. Furthermore, the couple had their divorce this past season as Detroit traded Urbina to Philadelphia.Nevertheless, Rodriguez and Urbina are the Best. Sports. Couple. Ever.last_img read more

Read More

NEC Begins Voter Roll Exhibition Today

first_imgCllr. Jerome George KorkoyaThe National Elections Commission (NEC) will today commence the exhibition of the Provisional Voter Roll at all 2080 Exhibition Centers (formerly Voter Registration Centers) across the country.The exercise is part of the electoral schedule according to Article 9.2 of the Voter Registration Regulations in keeping with section 3.6 of the New Elections Law of Liberia.The Provisional Registration Roll is a compilation of names, photos, center codes, ages, and other information of individuals who registered during the voter registration period from February 1 to March 14, 2017.The key exhibition activities are confirmation of applicant’s information; inclusion, where the opportunity is given to an applicant or registrant to be included on the Provisional Registration Roll if erroneously omitted; correction, where recorded information of an applicant is allowed to be changed by correction to set the proper information for the particular applicant or registrant. The exhibition will also show objection to inclusion, wherein the chance is given to those who have proof or evidence that points to the ineligibility of an applicant or registrant to be maintained on a voter roll.Each Exhibition Center across the country will have two electoral workers, the Exhibition Officer and the Clerk, to assist registered voters in viewing their particulars and conducting the exhibition process.“There are also 416 Electoral Supervisors across the country to monitor and coordinate the exhibition activities at the 2080 centers. They are working under the supervision of the Assistants and Electoral Magistrates throughout the 15 counties,” a press release said.The NEC has urged all Liberians in possession of valid voter registration cards to take advantage of the exhibition period which runs from today, June 12, to Saturday, June 17. The centers are open from 8 am to 5 pm daily.Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)last_img read more

Read More

Driver OK after oar flies through windshield on Alligator Alley

first_imgWEST BROWARD, FLA. (WSVN) – A paddle turned into a projectile when it went flying into an SUV’s front windshield along Alligator Alley, narrowly missing the driver, Friday.The woman, who was driving a white Chevy SUV, said she was behind a motor home that was pulling a boat when the oar crashed through the glass.Fortunately, she managed to duck out of the way, and it missed her by inches.Copyright 2019 Sunbeam Television Corp. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.last_img read more

Read More