Scouting Northern KentuckyThe Norse have had a rough time getting things going this season, compiling a 12-22 record that includes an abysmal 6-19 road record. The one thing that has gone well for the Norse this year has been their ability to produce at the plate. As a team, they are batting .275 with 36 home runs so far this season, including a pair of hitters with eight home runs and four regulars batting above .300. The team has scored a total of 211 runs, averaging 6.21 runs per game. Its star bat this season has been junior first baseman and pitcher Trey Ganns. Ganns has eight home runs, while his .310 batting average is sitting as the team’s second-highest among starters. Ganns, the team’s cleanup hitter, has demonstrated an acute ability to clean up the bases, leading the Norse with 32 RBIs this season.Scoring runs has not been an issue for the team. Rather, the issue has been keeping the opponents from scoring runs of their own. Across 287.2 innings the season, the Norse have posted a team ERA of 6.41, which ranks 260th out of 295 Division I programs. Pitchers have struggled to limit contact, having surrendered 364 hits this season (.370 opponents’ average). Finding More Consistency in the OffenseThe Buckeyes’ inability to keep the bats going for extended periods of time has been cited by coach Greg Beals as the chief issue for the team.After the team took two of three against Penn State with a combined 16 runs over the final two games of that series, the OSU offense mustered just two combined runs against a pair of midweek opponents in Cincinnati and Eastern Michigan, and was shut out by Michigan State in its first of the three games in the past weekend’s series. “We’ve been working really hard just with our offensive approach,” Beals said in a press conference last Thursday. “The two midweek games, we didn’t score enough runs to win the game, especially Wednesday night’s game, we pitched the ball really, really well.”Though his team has shown a lot of signs of struggle, Beals said he believes the talent is there for his team to start putting it all together, and he hopes his bats can click in opportune moments.“Each of the guys in our offensive lineup have shown signs of greatness, and we’ve got to find a way to get that out more consistently, and it’s an approach thing that we’ve got to do,” Beals said. “We’ve got to make sure that we are locked in on the pitches we are going to get and be consistent in that approach throughout an at-bat and be able to string some quality at bats together to produce some runs.”The Buckeyes hope to get that offense going again when they take on Northern Kentucky on Wednesday with first pitch scheduled for 6:35 p.m. Then-junior outfielder Tre’ Gantt is greeted by teammates outside the dugout after scoring a run over the weekend in the Big Ten/Pac-12 Challenge in Surprise, Arizona. Credit: Courtesy of Press Pros MagazineOhio State (15-21, 4-8) has been on the road for a while.It’s had some midweek home games mixed in there, but the past two weekend series have been on the road for the Buckeyes.Now OSU is getting a chance to enjoy some home cooking with its second nine-game homestand of the season, which will kick off on Wednesday with a matchup against the Northern Kentucky Norse (12-22, 6-6 Horizon League).The Buckeyes found little success the last time they played nine consecutive home games, amassing a 4-5 record and a 1-4 record in conference games.
Southampton goalkeeper Alex McCarthy believes the club shouldn’t be in their current situation of having to battle for Premier League survival.The Saints are currently seated in 19th position three points from safety and have already sacked Mark Hughes replacing him with Ralph Hassenhuttl.The former RB Leipzig becomes Southampton’s fifth managerial appointment in the space of four years, as they struggle to find some consistency, however, McCarthy believes the club are too big to get relegated.“I would probably be able to enjoy it more if we were higher up the table,” he said, according to the Telegraph.“Southampton is a massive club. We shouldn’t be in the situation that we’re in.”Solskjaer slams Man United’s draw: “We should have won” Andrew Smyth – August 31, 2019 Ole Gunnar Solskjaer was left to rue another missed opportunity as Manchester United were held to a 1-1 draw against 10-man Southampton.McCarthy also spoke about his improvement over the last 12 months, as he became a regular in the English National team setup.McCarthy made his first appearance in the Premier League last season during a 0-0 draw at Old Trafford last December and has permanently replaced Fraser Forster as the club’s first choice shot-stopper.He has been the mainstay in the goalkeeping department for the Saints in 2018, but the club have won only four Premier League games since the turn of the year.“It has been a very good year,” says the 29-year-old. “I’m happy. Playing week-in, week-out takes care of everything else. I can enjoy my life outside of football.”
The bill will be introduced during the upcoming legislative session set to convene tomorrow, January 16, in Juneau. Facebook0TwitterEmailPrintFriendly分享Senator Peter Micciche (R-K-Pen) has introduced a bill for the upcoming legislative session aimed at reducing the number of commercial set net fishers on the east side of the Cook Inlet. Senator Micciche emphasized that this is an introduction to a conversation, and is a ‘voluntary’ fleet reduction: “It’s at no cost to the state- we have discovered national and private funds that would help with it.” The bill also puts forward the question of a ‘commercial set net fishing permit buy-back program’. On March 1, 2019, the commission, and the Department of Natural Resources, will conduct an election among individuals qualified (certain set net fishers) on the question of whether to establish an entry permit buy-back program. Story as aired: Audio PlayerJennifer-on-set-net-bill-1.mp3VmJennifer-on-set-net-bill-1.mp300:00RPd The bill was introduced for the purpose of issuing entry permits and controlling entry into the commercial set net fishery on the east side of Cook Inlet, the commission would establish the area administered on December 31, 2018, as the Eastern Set Net Subdistrict of the Cook Inlet Central District as a distinct administrative area separate from the Cook Inlet Central District. The bill reads- “An Act relating to the powers of the Alaska Commercial Fisheries Entry Commission; requiring certain set net fishers to vote on the question of whether their entry permits shall be subject to a state buy-back program; establishing a buy-back program for certain set net entry permits; providing for the termination of set net site leases held by individuals who participate in the entry permit buy-back program; providing for a condition on future leases of certain state land; and providing for an effective date.” Senate Bill 135, according to Senator Micciche has a max 40% overall reduction. That would bring the ‘east set net fleet’ down to where it was prior to the eastern migration in the 80’s. Senator Micciche: “The numbers that came from back from the set netters polling themselves, were that 79.5% answered ‘yes’ that they would support the concept of a voluntary fleet reduction.” Senator Micciche: “This is a starting point in a conversation that began probably four years ago, when a group of set netters were looking for a solution. A gear reduction in the Cook Inlet, particularly in the east side set net fishery, if it were a win/win for all all would be a healthy outcome.”
The main entrance of the Anti-Corruption Commission headquarters in Dhaka. UNB File PhotoThe Anti-Corruption Commission (ACC) has decided to interrogate the bodyguard and driver of police’s suspended Deputy Inspector General (DIG) Mizanur Rahman on Sunday in connection with the allegation of bribery against him, reports UNB.Bodyguard Hridoy Hasan and driver Saddam Hossain were asked to appear at the ACC headquarters on 7 July, ACC public relations officer Pranab Kumar Bhattacharya said.Earlier on 1 July, the national anti-graft body sent a letter to DIG Mizan asking him to turn up at its office at 10:00am on 8 July for interrogation as he skipped the grilling on 1 July citing personal reasons.A private TV channel recently reported that Mizan gave Tk 4 million to ACC director Khandaker Enamul Basir to get clean chit in a corruption case.Top-ranking police officer Mizanur Rahman amassed Tk 32.8 million illegally between 1998 and 2018, according to a probe conducted by the ACC.The additional commissioner of Dhaka Metropolitan Police (DMP) made the money by taking bribes and committing corruption.He was withdrawn on 9 January last year following an allegation of threatening a female news presenter of a private television channel.He had also reportedly married a woman forcibly and tortured her. Mizan allegedly picked up the 25-year-old woman in July, 2017 and forcibly married her.
(Phys.org)—A pair of researchers at Duke University has built a library of protein data that outlines the specific amino acid sequences that control changes of many elastin proteins. In their paper published in the journal Nature Materials, Felipe García Quiroz and Ashutosh Chilkoti describe their research, the making of their library, and their belief that what they have created will help in the development of new synthetic designs for possible use in medical applications. Citation: Researchers develop a library of elastin-like proteins to help in creating synthetic designs (2015, September 23) retrieved 18 August 2019 from https://phys.org/news/2015-09-library-elastin-like-proteins-synthetic.html Proteins assemble and disassemble on command This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. More information: Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers, Nature Materials (2015) DOI: 10.1038/nmat4418AbstractProteins and synthetic polymers that undergo aqueous phase transitions mediate self-assembly in nature and in man-made material systems. Yet little is known about how the phase behaviour of a protein is encoded in its amino acid sequence. Here, by synthesizing intrinsically disordered, repeat proteins to test motifs that we hypothesized would encode phase behaviour, we show that the proteins can be designed to exhibit tunable lower or upper critical solution temperature (LCST and UCST, respectively) transitions in physiological solutions. We also show that mutation of key residues at the repeat level abolishes phase behaviour or encodes an orthogonal transition. Furthermore, we provide heuristics to identify, at the proteome level, proteins that might exhibit phase behaviour and to design novel protein polymers consisting of biologically active peptide repeats that exhibit LCST or UCST transitions. These findings set the foundation for the prediction and encoding of phase behaviour at the sequence level. Journal information: Nature Materials © 2015 Phys.org Explore further Proteins are organic compounds essential to all living organisms, they are especially prevalent in components that have structure, such as muscle, skin, hair, etc. They provide structure by self-forming into different shapes under different conditions, two of which are solubility and temperature. Proteins are made of sequences of amino acids—the order and type of which drive the shape of the protein when certain conditions are met. Scientists still do not quite understand how proteins self assemble into the specific 3D shapes they take, nor which amino acids lead to which shapes, or indeed, how the order in which they exist contributes to those shapes. To help provide a better understanding of how it all works, Quiroz and Chilkoti set about building a library of all the known elastin-like proteins, along with the shapes they take under different conditions. They based it on the sequences of five key amino acids found in the fibrous protein typically found in connective tissue, such as muscles. They then set about testing each entry in the library by growing samples of E. coli engineered to produce proteins that folded into different shapes under different conditions. Most specifically noted was under which conditions the proteins shifted from being soluble to non-soluble and vice-versa. That work led them to developing a set of rules that loosely defined which amino acid sequences would result in which shapes under which conditions.The research duo acknowledge that their rules are more like guidelines, but suggest the basis of what they have built can not only be made stronger with more research by them and others, but can be used to assist in creating synthetic proteins for use in developing targeted drugs. One example would be protein capsules that remain insoluble inside the body until a certain condition is met, at which point, a medication would be released.
Kolkata: The Trinamool Congress party office in Contai was ransacked and some vehicles parked outside set ablaze by alleged BJP supporters on Tuesday evening.Suvendu Adhikari, the state Transport minister, stated that BJP supporters, after attending Amit Shah’s rally, ransacked the party office along with several nearby shops. Some bikes were also set on fire. There were long queues of cars on Contai bypass and the miscreants broke the windscreens of many of them that were caught up in the traffic jam. Also Read – Speeding Jaguar crashes into Mercedes car in Kolkata, 2 pedestrians killed”We do not believe in violence. Or else, we could have taught them a lesson. Such incidents are uncalled for and unfortunate. BJP is losing ground everywhere and such incidents reflect the nervousness of the party,” said Suvendu. He further added: “The BJP should first concentrate on defending its government at the Centre. The people of this country have already made up their mind to vote them out.” “They (BJP) should stop lecturing others on democratic values and people’s rights. Had they provided good governance, they would not have been voted out in three Hindi heartland states (Rajasthan, Chhattisgarh and Madhya Pradesh in the December Assembly polls)”, he said. Meanwhile, Trinamool MP Sisir Adhikari alleged that the CPI(M) supporters who have recently joined the saffron party were behind the Contai ransack. The TMC will take out a rally condemning the incident on Wednesday.
Kolkata: The Mamata Banerjee government on Tuesday appointed an IAS officer to take charge of the recently constituted monitoring cell for proper implementation of government schemes and to probe allegations of taking money (referred to as cut money) against giving benefits under the schemes.IAS Barun Ray, the 1992 batch officer who has been given the charge of the cell, was posted as commissioner, Malda division. Ray has also been transferred to the post of commissioner, Burdwan division. Also Read – Rs 13,000 crore investment to provide 2 lakh jobs: MamataHe will hold the charge of OSD at the Chief Minister’s Office (CMO) in the rank of principal secretary in charge of Monitoring of Programme Implementation and Grievance Cell. Chief Minister Mamata Banerjee had opened the cell for “Programme Implementation of Government Schemes and Redressal of Grievances/Complaints” and announced a toll-free number for lodging complaints. The cell has received 1,500 complaints so far. Once a beneficiary from the districts raises his/her issue with the CMO through email at firstname.lastname@example.org, it will be thoroughly examined and replied to within 10 days. Also Read – Lightning kills 8, injures 16 in stateThe new and unprecedented approach is aimed at refining the whole delivery mechanism system of the schemes in the state. The fundamental objective of the move is to reach out to the marginalised benefici- aries. Colonel (retired) Diptangshu Chowdhury, who heads the cell, has visited the districts and interacted with the beneficiaries who have been denied government welfare scheme benefits or harassed while receiving such benefits. The state government has asked police superintendents to initiate cases on complaints of accepting cut money under Section 409 of the Indian Penal Code, which calls for a maximum punishment of life imprisonment.